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Post by Romy & Frankie on Oct 11, 2023 13:12:01 GMT -7
I am glad to hear that the pred taper is going well at this point. Since Goeff is still taking gabapentin, it will take longer to know if the spinal cord swelling is truly gone.
I don't think there has been a lot of research on the Assisi loop, but some of our members and one of our former moderator’s have used it.
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Post by Uecker & Goeff on Oct 18, 2023 21:52:37 GMT -7
10-18-23. Update on Geoffrey. We did the 10 days of prednisone at 1x a day, everything seems to be going well. Tomorrow 10-19 he will not get a prednisone as we are starting the every other day for 10 days dosage. [MED LIST/HISTORY- Moderator's Note. Please do not edit 16lbs 10-11y.o 9/23 wobbly, right rear paw knuckling Dex inj 9/23 prednisone as of 9/24: 5mgs 2x/day for 5 days, 9/29 test taper for: 9/30 pain / 9/30▲wobbly neuro as of 9/30: 5mgs 2x/day for ▲11 days, Tues 10/10 test taper: final Dose 11/8. gabapentin 100mgs 2x/day thyro-tabs 2x/day lactulose 2x/day ]
Was the Assisi Loop a recommended treatment?
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PaulaM
Moderator.
Member since 2007: surgery, conservative . Montana, USA
Posts: 19,928
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Post by PaulaM on Oct 19, 2023 10:31:21 GMT -7
Uecker, the true situation of existing pain will only be learned when the pain masking pain med gabapentin stops. Do let us know when gabapentin will be stopped or back down in mgs/times per day. The Assisi loop might help with pain, but we do not know of any specific well-designed research studies to support it and point you to. What we know is if there is pain then the IVDD meds are what are needed during a disc episode. Right now you report with the gabapentin blindfold on all "seems" to be going well. Seems prudent to not to jump of investigating the Assisi, until you know if pain (swellihg) even still exists. If you were to see pain with stop of gabapentin and the EOD pred, that would signal to get pred back on board for further work on swelling.
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Post by Uecker & Goeff on Oct 30, 2023 21:07:38 GMT -7
10-30-23 update. Thank you so much for the responses above, I did not see there was 2 of them. The tapering is going well w/ the prednisone. No pain, no paw knuckling. We have to do 10 days every other day - and today [10/30] was the 6th pill, so we would have 4 more pills to go [final pred dose on 11/8]. Will keep you posted on the medication changes once vet advises.
I did notice he has a rash on his upper inside leg/groin area though, not sure if this is from the tapering of prednisone? maybe a yeast infection?
Thank you for both for the information on the Assisi loop, I was wondering more about it as it was a suggestion given. The time and information given is greatly appreciated.
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PaulaM
Moderator.
Member since 2007: surgery, conservative . Montana, USA
Posts: 19,928
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Post by PaulaM on Oct 31, 2023 8:43:24 GMT -7
Uecker, when will pain masking gabapentin 2x/day be full stopped? There is no idea of the truth about existence of pain while the gabapentin pain mask of 100mgs 2x/day is on board. The rash could be from a number of things. Keep an eye on it that no broken skin happens where bacteria can enter the body. Is he free from urine on skin/fur after peeing? Wipe him down after potty time with green tea just to make sure skin is clean. Marjorie's tip: Brew up a pot of decaf green tea. Let it cool. Then use a tea dampened washcloth to gently wipe belly and legs. Tea is mild with acidifying, antibacterial properties. It neutralizes urine on skin and fur to avoid urine scald rashes. Store tea in fridge and slightly warm before use. Add a hand sprayer to white vinegar bottle to disinfect. Vinegar removes the urine ammonia smell from floors and fabrics.
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Post by Uecker & Goeff on Nov 1, 2023 7:39:14 GMT -7
The vets are going to send a prescription to the pharmacy cefpodoxime 100mg so I have some on hand in case it's needed.
[Oct 31, 2023 at 8:07pm]: Thank you. I checked w/ the vets and she wrote back its a bacterial skin infection, prednisone can decrease the immune system and possibly had an outbreak of a skin infection. We can apply Neosporin or pick up a mousse with an antibiotic and apply to the skin. Or if it spreads to add in an oral antibiotic.
I have not felt him wet from urine at all on his skin. He has been going potty on his own either outside or on a potty pad.
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Post by Uecker & Goeff on Nov 6, 2023 23:39:05 GMT -7
11-7 update. He was doing wonderfully, even tried to play etc but then more
issues arose on 11-1. We tried to lower the gabapentin to 1x a day and that did not go well on 11-1. We did the prednisone and gabapentin in the morning.
Did not do his gabapentin w / dinner dose. A couple hours later, he threw up and had diarrhea all night (every 2 hours he was going until 9am the next day). The vets don't believe 100mg of gabapentin could cause a withdrawal and are not sure what happened. bc of his stomach issues - we need to wait. We gave him a gabapentin that night at around 10pm and continued w/ the 2x a day dosing. (Did not do the lactulose for the next few days 11-1 to 11-6). Only on his canned dog food for now. He did have solid poop the next day 11-2.
We also did not pick up the antibiotics, the vet decided to try a mousse called ✙Douxo S3 for the skin infection to not upset his stomach more. Picked the mousse up on Friday 11-3 and started that right away. The skin infection is getting better. I have noticed allergy like symptoms also - ear itching/biting paws, which he never did before. Not sure what is going with that. If the meds are weakening the immune system too much, if the meds are interacting somehow and his thyroid? etc. Vet thinks allergies? He has never had allergies before. Also today 11-7 keeping an eye on urine - I noticed today he has been peeing less, and his morning urine is light yellow vs his normal dark yellow color. Vet said to keep an eye on that for a day or 2, may need to bring in a urine sample to check a urinalysis.
Also had to add back in the ✙lactulose tonight as his poop was too hard again.
[MED LIST/HISTORY- Moderator's Note. Please do not edit 16lbs 10-11y.o 9/23 wobbly, right rear paw knuckling Dex inj 9/23 prednisone as of 9/24: 5mgs 2x/day for 5 days, 9/29 test taper for: 9/30 pain / 9/30▲wobbly neuro as of 9/30: 5mgs 2x/day for 11 days, Tues 10/10 test taper final dose 11/8: _ pain _ neuro gabapentin 100mgs 2x/day thyro-tabs 2x/day ✙Douxo S3 for the skin infection ✙lactulose 2x/day ]
We have 1 more dose of prednisone [11/8] tomorrow morning. I will be adding in milk thistle hopefully later this week as I think his organs/system really needs it. These meds have been rough. also add back in the yogurt for probiotics.
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PaulaM
Moderator.
Member since 2007: surgery, conservative . Montana, USA
Posts: 19,928
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Post by PaulaM on Nov 7, 2023 11:15:48 GMT -7
Uecker, what a complicated case Geoff has with so many issues. Good job on keeping on top of things plus having a good vet to work with.
Asking again....With the final every other day dose of Pred to be on 11/8, will gabapentin 100mgs 2x/day also be stopped on 11/8?
Typically a dog would be off of all meds (pred, pain relievers) at minimum of 7 days before a graduation on expected 11/18. Off all meds and no pain nor any new neuro diminishment would give proof all painful inflammation around the spinal cord is actually resolved.
From what I read, the bacteria in yogurt is not the usual array of bacteria in a dog's gut. So if you are wanting to replenish a dog's gut bacteria, you may want to seek probiotics designed for a dog. Your vet or on-line can be a source.
Fingers crossed on stop of final pred dose and no pain meds on board, Goeff, will be set up for expected graduation day on Nov 18. We'll have lots of information to help you safely re-introduce activity and many tips for living many happy years ahead with your IVDD Goeff.
Also with the stop of pred, hopefully Geoff, can overcome skin and other issues that might be related to being on pred. Thank you and please continue to keep us posted.
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Post by Uecker & Goeff on Nov 13, 2023 12:27:32 GMT -7
Thank you so much! 11-13 update.
The vet wanted to wait a couple weeks on the gabapentin decrease until his stomach issues calmed down. We are not certain what the issue was that day. Just strange it appeared the same day as we tried to do the decrease. He is doing better with his stomach issues now , I am checking with the vets to see when we can do the decrease - this week or if we need to wait another week.
How is the gabapentin decrease normally done? Last time we did the 100 mg capsule 1x a day vs 2x a day (did the morning dose w/ breakfast and skipped the night dose w/ dinner). the vets did mention if that doesnt go well again... we could open the 100 mg capsule and pour half in w/ breakfast and half in w/ dinner to do a decrease that way. Sam's club did not have any 50 mg capsules available in gabapentin.
He still has the rash and I am applying the mousse which she said could take a few weeks to resolve.
Thank you so much for all your time and help!!
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PaulaM
Moderator.
Member since 2007: surgery, conservative . Montana, USA
Posts: 19,928
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Post by PaulaM on Nov 13, 2023 13:07:40 GMT -7
Uecker, after watching years of owner reports come in, each vet seems to have their own way to back off of gabapentin based on their knowledge of the dog's needs/case issues (a seizure dog, rebound pain or other). Just mentioning again... that the Nov 18th expected graduation, should delay til off of all pain meds for a week before releasing Geoff to a slow and gradual re-introduction back to family life and activity. So we will be watching for your report of when he is off all pain meds. Then we'll have lots of info to share with you about Graduation. Gabapentin is extremely bitter to be mixing into his food. One taste of it and Geoff will take a long time to not be suspicious and trust you again. Here is how to dose gabapentin in capsules. Unfortunately, the smallest size gabapentin capsules are the 100mg ones! The powder in the capsules can be easily divided: As an example if Rx'd approx 30mg of gabapentin then: Divide the 100mg capsule powder into 3 equal parts by dumping into a creased pieced of paper. With a razor blade move the powder into 3 equal piles. Store the remainder of the powder piles in one of those 7-day pill boxes with a lid for each day. NOTE: Make sure you do not transfer any of the bitter dust from your fingers to the outside of the pill treat. Wash your hands! I mash a piece of banana, form a ball, make an indentation. Transfer one powder dose into banana well and close up. If necessary drape a piece of thin deli meat around ball for further tastiness! Another alternative is to purchase a small qty of the empty clear capsules from your local health food store to place the necessary dose of powder in. Then you can pill as you normally have been doing for a capsule. NOTE: you may need help to hold the half capsule upright as you funnel the powder from the folded/creased paper into the capsule.
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Post by Uecker & Goeff on Nov 14, 2023 10:38:00 GMT -7
11-14 update. We started the decrease this morning on the▼gabapentin. we are doing half the capsule in the morning, and half at night. [MED LIST/HISTORY- Moderator's Note. Please do not edit 16lbs 10-11y.o 9/23 wobbly, right rear paw knuckling Dex inj 9/23 prednisone as of 9/24: 5mgs 2x/day for 5 days, 9/29 test taper for: 9/30 pain / 9/30▲wobbly neuro as of 9/30: 5mgs 2x/day for 11 days, Tues 10/10 test taper, final dose 11/8: _ pain _ neuro gabapentin ▼50mgs 2x/day thyro-tabs 2x/day Douxo S3 for the skin infection lactulose 2x/day ]
Thank you for the information, its greatly appreciated and very helpful! Thank you!
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Post by Uecker & Goeff on Nov 15, 2023 11:26:33 GMT -7
11-15 update. Decrease on gabapentin went well yesterday, no illness this time. No signs of pain, no paw knuckling.
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Post by Uecker & Goeff on Nov 27, 2023 15:22:28 GMT -7
11/27 update; another ▼gabapentin decrease today. Doing 25mg morning / 25 mg at night.
[MED LIST/HISTORY- Moderator's Note. Please do not edit 16lbs 10-11y.o 9/23 wobbly, right rear paw knuckling Dex inj 9/23 prednisone as of 9/24: 5mgs 2x/day for 5 days, 9/29 test taper for: 9/30 pain / 9/30▲wobbly neuro as of 9/30: 5mgs 2x/day for 11 days, Tues 10/10 test taper, final dose 11/8: _ pain _ neuro gabapentin ▼25mgs 2x/day thyro-tabs 2x/day Douxo S3 for the skin infection lactulose 2x/day ]
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PaulaM
Moderator.
Member since 2007: surgery, conservative . Montana, USA
Posts: 19,928
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Post by PaulaM on Nov 27, 2023 15:36:02 GMT -7
Hope you will add your observations with being off of Pred and now decreasing gabapentin......
Is there a final dose date projected when gabapentin will stop?
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Post by Uecker & Goeff on Nov 29, 2023 9:52:15 GMT -7
11-29. He is doing wonderful, No signs of pain, no paw knuckling.
Rash is still lingering but getting better.
no projected [gabapentin] dates, we are taking the decrease very slow with the gabapentin bc of the illness when we decreased the first time.
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PaulaM
Moderator.
Member since 2007: surgery, conservative . Montana, USA
Posts: 19,928
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Post by PaulaM on Nov 29, 2023 15:55:27 GMT -7
Uecker. sounds very promising with Gabapentin 2x/day (25mgs) that all swelling might be gone. We look forward to the day he is fully off gabapentin so you can begin a slow introduction back to family life and get those muscles working, strengthening bones with exercise. We'll have lots of valuable tips for doing this safely as well as living with your IVDD dog for many happy years ahead. Let us know when you know about the proposed stop of gabapentin.
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Post by Uecker & Goeff on Dec 12, 2023 16:51:01 GMT -7
12-12 update, he is doing very well. No signs of pain or paw knuckling. We are down to 1x (with breakfast) a day ▼gabapentin at 12.5mg.
[MED LIST/HISTORY- Moderator's Note. Please do not edit 16lbs 10-11y.o 9/23 wobbly, right rear paw knuckling Dex inj 9/23 prednisone as of 9/24: 5mgs 2x/day for 5 days, 9/29 test taper for: 9/30 pain / 9/30▲wobbly neuro as of 9/30: 5mgs 2x/day for 11 days, Tues 10/10 test taper, final dose 11/8: _ pain _ neuro gabapentin ▼12.5mgs ▼1x/day thyro-tabs 2x/day Douxo S3 for the skin infection lactulose 2x/day ]
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PaulaM
Moderator.
Member since 2007: surgery, conservative . Montana, USA
Posts: 19,928
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Post by PaulaM on Dec 12, 2023 19:43:41 GMT -7
Uecker, such good news that now getting very close to last dose of gabapentin. Do you have a date PROOF with the last dose of gabapentin? We'll be watching to learn when Goeff can graduate and begin a safe and slow introduction back to life!
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Post by Uecker & Goeff on Dec 20, 2023 16:57:00 GMT -7
12-20-23 update. Thank you! are the tips listed on the website? He's doing really well on low dose 1x a day gabapentin. No signs of pain or paw knuckling. Next week we will be able to try every other day 1x a day gabapentin and see how things go. We really appreciate all your time and help!! Thank you so much!!
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PaulaM
Moderator.
Member since 2007: surgery, conservative . Montana, USA
Posts: 19,928
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Post by PaulaM on Dec 20, 2023 19:10:06 GMT -7
Once Uecker is off all meds and no signs of pain/neuro, then we are in position to give you and outline with comments that pertain to Uecker on graduation day. We await hearing the date of the last gabapentin med dose. Gabapentin does not need to be given every other day... EOD is just used for a steroid in order to signal the body to make its own steroid hormone. Why is gabapentin dragging out so long for yet another week?
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Post by Uecker & Goeff on Dec 28, 2023 10:43:36 GMT -7
12-28-23 update. He was doing so well. We took out the gabapentin and weird things keep happening - the first time we took out the gabapentin [11/1] he became super ill [when gabapentin stopped). [withdraw symptoms, we had to take his decrease extremely slow. He was doing a type of shaking, vomiting and very very bad diarrhea.] Yesterday we took out the [12/27 stopped] gabapentin and • he ended up tripping • and then started to limp [pain] on his front left leg last night. He was holding his f.l. paw out [pain] and up last night and limping, not putting any weight on it, like he hurt his paw. We ended up doing the low dose gabapentin last night and this morning (12.5mg). The vets want him to go back up on the ▲gabapentin to the 100mg 2x a day for a week and see how things go as they believe that also made his back sore.
[MED LIST/HISTORY- Moderator's Note. Please do not edit 16lbs 10-11y.o 9/23 wobbly, right rear paw knuckling 12/27 stopped gabapentin, dog tripped, not bearing weight on FRONT left paw Withdrawal symptoms if full stop of gabapentin. Dex inj 9/23 prednisone as of 9/24: 5mgs 2x/day for 5 days, 9/29 test taper for: 9/30 pain / 9/30▲wobbly neuro as of 9/30: 5mgs 2x/day for 11 days, Tues 10/10 test taper, final dose 11/8: 12/27 l.f. paw pain _ neuro gabapentin ▲100mgs ▲2x/day til 1/5/24 thyro-tabs 2x/day Douxo S3 for the skin infection lactulose 2x/day ]
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Post by Romy & Frankie on Dec 28, 2023 14:22:35 GMT -7
It is concerning that Goeff has started limping and holding his paw up. Are you confident that he injured his paw when tripping? Just to make sure I understand, the vet thought that when he tripped, he also made his back sore?
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Post by Uecker & Goeff on Dec 28, 2023 17:13:01 GMT -7
I know it is very concerning! My poor boy! I thought he may have broke a nail like his dew claw with how he was holding his paw up/ limping w/ his front leg but I couldn't see any broken nails. He is putting weight on that paw/leg [12/28]today.
She thinks the trip and limping may have made his back sore as well and to increase the gabapentin to help and see how he does in the next few days. I will increase the gabapentin tonight and see how he does. I am so worried.
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PaulaM
Moderator.
Member since 2007: surgery, conservative . Montana, USA
Posts: 19,928
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Post by PaulaM on Dec 28, 2023 18:44:38 GMT -7
What is the evidence (observation) that you and your vet see that tells the back is sore?
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Post by Uecker & Goeff on Dec 28, 2023 20:58:29 GMT -7
She thought his back was bothering him/sore by how he is walking. When he started holding up his paw and limping last night he started shaking while he would walk. When he is laying down, he doesn't do any shaking and He is not stiff nor has the hard stomach like the first time. she said she wants to try the increase in gabapentin first a few days and see if he continues to improve. If not, she will add back in the prednisone. Any thoughts? Thank you so much for all your help, I can't believe this is happening.
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PaulaM
Moderator.
Member since 2007: surgery, conservative . Montana, USA
Posts: 19,928
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Post by PaulaM on Dec 29, 2023 9:00:27 GMT -7
Uecker, continue to mention how the front left paw/leg does with bearing weight and any other signs of change Geoff might show about pain or with neuro.
Hope to hear the 100 mgs gabapentin 2x/day continues to give relief from was the cause of the pain.... tripping/muscle sorness, etc.
The test will be when gabapentin stops. Pain meds block pain, so you will need the ability to get a clear picture if pain exists or all gone when gabapentin stops.
What are the details/observations about the stop of "gabapentin he became super ill"
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Post by Uecker & Goeff on Dec 29, 2023 10:43:39 GMT -7
The first time we tried to stop the gabapentin he went thru what seemed to be withdraw symptoms, we had to take his decrease extremely slow. He was doing a type of shaking, vomiting and very very bad diarrhea.
We were doing that low dose gabapentin for 2 weeks at 12.5mg at 1x a day w/ breakfast and no issues.
When we tried to stop the gabapentin again, now we ended up with his front paw/leg issue. His back legs have been fine, no paw knuckling.
We did increase the gabapentin per the vets request. He is doing much better this morning. He wants to walk around. The front leg/paw he is keeping weight on it and no signs w/ any neuro on any of the legs/paws.
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Post by Romy & Frankie on Dec 29, 2023 14:03:35 GMT -7
I am glad that Geoff is not showing any signs of pain and wants to walk around with the increase in gabapentin.
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Post by Uecker & Goeff on Dec 29, 2023 19:41:33 GMT -7
Thank you. We are glad the gabapentin is helping too. The vet said it is a possibly the IVDD acting up, and to keep him on the higher dosage for a week, and then very slowly go down again and He may need to stay on the low dose gabapentin for now.
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PaulaM
Moderator.
Member since 2007: surgery, conservative . Montana, USA
Posts: 19,928
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Post by PaulaM on Dec 30, 2023 21:22:20 GMT -7
Uecker, gosh this is a baffling front leg issue Geoff is dealing with.
Your vet may have the right idea, that Geoff just may have to stay on low dose gabapentin 12.5mgs long term.
So we must wait on your vet's instruction as to when it will be safe for Geoff to phase in very slow and gradual physical activity.
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